Should the definition of CKD be changed to include age-adapted GFR criteria? YES

Should the law on assisted dying be changed? Yes.

The case for legalising assisted dying for people with terminal illness is easily stated. Unbearable suffering, prolonged by medical care, and inflicted on a dying patient who wishes to die, is unequivocally a bad thing. It is one of the fundamental principles of medicine that you should be allowed to determine what is in your own best interest when you are of sound mind. Nobody else’s views sh...

[Should the resuscitation guidelines be changed?].

Should the consensus guidelines' specific criteria for the diagnosis of invasive fungal infection be changed?

The introduction of a standardized set of criteria to define invasive fungal infections has fulfilled a need. The criteria make comparisons between various clinical studies more easy and facilitate discussions of trial designs. However, application of the criteria in practice has indicated that some criteria for possible disease (in particular, antibiotic-resistant fever during neutropenia) are...

Yes, Managers Should Be Paid like Bureaucrats

Corporate scandals, reflected in excessive management compensation and fraudulent accounts, cause considerable damage. Agency theory’s insistence on linking the compensation of managers and directors as closely as possible to firm performance is a major reason for these scandals. They cannot be overcome by improving variable pay for performance, as selfish extrinsic motivation is reinforced. Ba...

Massive haemoptysis: the definition should be revised.

We thank L. Mascitelli and colleagues for their interesting comments about the role of the renin–angiotensin system in severe chronic obstructive pulmonary disease. Our review [1] was intended to provide guidance on current established therapies rather than consider potential future treatment options and hence we did not include a comment relevant to this interesting but, as yet, unproven treat...